Math 8803/4803 HEH: Discrete Mathematical Biology





Spring 2008

Day
Time
Room
Mon, Wed, Fri
9:05 - 9:55
Skiles 270

Taught by: Prof. Christine Heitsch


Description

Lectures

Projects

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Description

This course will focus on the interaction between combinatorics and molecular biology, with particular emphasis on DNA and RNA sequences. This is a rapidly developing research area, accessible to advanced undergraduates and introductory graduate students, at the intersection of the mathematical, computational, and biological sciences.

We will cover recent combinatorial results, as well as current open problems needing new advances in discrete mathematics and its applications, for the following topics in computational molecular biology:

DNA --- fragment assembly, sequence alignment and comparison, motif discovery, optical mapping, word design, and chromosome rearrangements.

RNA --- comparative sequence analysis, secondary structure prediction, inverse folding, pseudoknots, and three-dimensional alignment and comparison.

If time permits, we will touch on other topics such as phylogenetics and biological networks.



Lectures



Project Presentations



Handouts



Assignments



Resources



C. E. Heitsch
Spring 2008